Often, a subacute presentation of worsening symptoms occurs over several days.2,3
In a clinical study of patients admitted to the hospital with heart failure, worsening of dyspnea and edema was noted on average 8 and 12 days prior to hospitalization, respectively.*4
When oral diuretics fail, clinicians often rely on giving IV diuretics—typically in the hospital, outpatient heart failure clinic, or infusion center.5,6
The caregiver’s own health can be negatively impacted by
*N = 83 patients, of which 98% experienced dyspnea and 77% developed edema as a symptom associated with decompensation.
Is FUROSCIX right for your heart failure patients?
Learn MoreReferences: 1. Vasko MR, Cartwright DB, Knochel JP, Nixon JV, Brater DC. Furosemide absorption altered in decompensated congestive heart failure. Ann Intern Med. 1985;102(3):314-318. doi:10.7326/0003-4819-102-3-314. 2. Heidenreich PA, Bozkurt B, Aguilar D, et al. 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2022;145:e895-e1032. doi: 10.1161/CIR.0000000000001063. 3. Greene SJ, Mentz RJ, Felker GM. Outpatient worsening heart failure as a target for therapy. JAMA Cardiol. 2018 March 01;3(3):252-259. doi:10.1001/jamacardio.2017.5250. 4. Schiff GD, Fung S, Speroff T, McNutt RA. Decompensated heart failure: symptoms, patterns of onset, and contributing factors. Am J Med. 2003;114(8):625-630. doi:10.1016/s0002-9343(03)00132-3. 5. Sica DA, Muntendam P, Myers RL, et al. Subcutaneous furosemide in heart failure: pharmacokinetic characteristics of a newly buffered solution. JACC Basic Transl Sci. 2018;3(1):25-34. Published 2018 Feb 7. doi:10.1016/j.jacbts.2017.10.001. 6. Mullens W, Damman K, Harjola VP, et al. The use of diuretics in heart failure with congestion - a position statement from the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail. 2019;21(2):137-155. doi:10.1002/ejhf.1369. 7. Solomon SD, Dobson J, Pocock S, et al. Influence of nonfatal hospitalization for heart failure on subsequent mortality in patients with chronic heart failure. Circulation. 2007;116(13):1482-1487. doi:10.1161/CIRCULATIONAHA.107.696906. 8. Mills RM. The heart failure frequent flyer: an urban legend. Clin Cardiol. 2009;32(2):67-68. doi:10.1002/clc.20404. 9. Nieminen MS, Dickstein K, Fonseca C, et al. The patient perspective: quality of life in advanced heart failure with frequent hospitalisations. Int J Cardiol. 2015;191:256-264. doi:10.1016/j.ijcard.2015.04.235. 10. Greene SJ, O’Brien EC, Mentz RJ, et al. Home-time as a novel post-discharge outcome for patients hospitalized with heart failure. J Am Coll Cardiol. 2018 June 12;71(23):2643-2652. doi:10.1016/j.jacc.2018.03.517. 11. Hwang B, Fleischman KE, Howie-Esquivel J, et al. Caregiving for patients with heart failure: impact on patients’ families. Am J Critical Care. 2011;20(6):431-441.