FLUID OVERLOAD: A VICIOUS CYCLE

Ongoing fluid overload is connected to: 

Ongoing fluid overload is connected to: 

  • CKD progression1
  • Cardiovascular complications—especially congestive heart failure3
  • Reduced quality of life4
  • Higher healthcare costs5,6
  • Significantly increased patient mortality7

the role of bioavailability in treating fluid overload

the role of bioavailability in treating fluid overload

Gut edema caused by fluid overload can impede the absorption of oral diuretics, compromising their bioavailability.3,12,13 Despite full or maximum oral dose therapy, fluid overload (and related symptoms) may continue or worsen.4

While IV loop diuretics can avoid intestinal absorption challenges and offer greater bioavailability, their administration often necessitates hospitalization with its associated patient risks and burdens.4

As soon as your CKD and cardiorenal patients experience signs and symptoms of fluid overload despite maintenance diuretic therapy,

it’s time for FUROSCIX.

efficiently resets fluid levels

FUROSCIX reaches therapeutic plasma furosemide levels within 30 minutes.3,16*

see more about furoscix efficacy

validated for patient ease of use

FUROSCIX was designed for and tested to ensure successful patient use in the comfort of home.17

see more about furoscix use

*

Based on mean ± SD 30-minute plasma concentration of 600 (± 209) ng/mL.3

GFR=glomerular filtration rate; SD=standard deviation.

FUROSCIX delivers a fixed 80 mg of medication over 5 hours18:

  • 30 mg in the first hour
  • 12.5 mg per hour for the next 4 hours

FUROSCIX is indicated for the treatment of edema (i.e., congestion, fluid overload, or hypervolemia) in pediatric patients who weigh at least 43 kg and adult patients with chronic heart failure or chronic kidney disease (CKD), including the nephrotic syndrome.

FUROSCIX is not for chronic use and should be replaced with oral diuretics as soon as practical.

patients can benefit from furoscix as soon as fluid overload signs or symptoms present3,4,14,18

consider furoscix at the onset of fluid overload signs and symptoms, such as19:

RAPID WEIGHT GAIN

Peripheral Edema

DYSPNEA

Pulmonary congestion/edema

TROUBLE SLEEPING

or lying down

Early intervention

Encourage your patients to recognize and report symptoms of fluid overload as soon as they present. This allows you the opportunity to intercept episodes of fluid overload before they worsen.